I have a client who, luckily, has an extremely large living room. The only problem is...that above the sofa, we are having problems finding are that we love that fills the space. It's a pretty big wall. So, I'm pushing for a grouping of framed smaller art pieces that go together.
It makes such an impact and the frames add an architectural detail which is just a bonus to the artwork.
I also like them placed in order, not arranged in random order. There is something grand about an organized arrangement that makes the room more dramatic and bold.